Comparative Effectiveness of Antihypertensive Therapeutic.

The current treatment of essential hypertension is based on the following concepts: (1) a single cause has not been identified. Indeed, essential hypertension appears to be a multifactorial disorder. Specific therapy, therefore, is not possible;1 (2) the homeostatic mechanisms that regulate blood pressure are intact in hypertensive subjects and responsive to physiologic and chemical.

Start studying Antihypertensive drug classifications. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

Title: Microsoft Word - Q24 Classify antihypertensive agents by their mechanism of action, with a brief outline of each mechanism, and an example of a drug in each class (Sept 2010).docx.

US Custom Essay Service at Your Door Step!!! The global essay writing service delivering pro-quality help and secure experience to customers worldwide.

In addition, ARBs are effective antihypertensive drugs for a BP-independent effect on arterial stiffness, mainly through long-term arterial remodeling and reduction of arterial wall fibrosis. In long-term controlled studies, the ARBs olmesartan and valsartan had the capacity to reverse aortic stiffening independently of changes in BP. 5.2.

The researchers developed a comprehensive framework to compare effectiveness and safety of antihypertensive drugs and outcomes from observational data from 4.9 million patients. Using the framework, they conducted a systematic, large-scale study comparing relative risk for 3 primary and 6 secondary effectiveness outcomes and 46 safety outcomes among first-line classes.

Alternative managmentb of hypertensive patient among the lower economic class Hypertensive patients of the lower economic class prefers non-conventional methods of managing blood pressure levels. Hypertension is one of the most common non-communicable diseases worldwide affecting up to 800 million (or 20%) of the world’s adult population.

Patients with hypertension must take antihypertensive drugs on a long-term basis. Although such drugs cannot give a radical cure, they can prevent heart failure, kidney failure and acute stroke induced by hypertension and delay the development of atherosclerosis by controlling the blood pressure. Generally speaking, antihypertensive drugs must be.

Some antihypertensive drugs, most notably beta-blockers, depress heart rate and contractility (this decreases stroke volume) by blocking the influence of sympathetic nerves on the heart. Calcium-channel blockers, especially those (non-dihydropyridines) that are more cardioselective, also reduce cardiac output by decreasing heart rate and contractility.

Common side effects of these diuretics include nausea, headache and stomach upset. ACE inhibitors -- the short form for angiotensin-converting-enzyme inhibitors -- lower blood pressure by preventing a chemical, angiotensin II, from being secreted and causing blood vessels to constrict.

Antihypertensives are medications that lower blood pressure, reducing strain on, and damage to, the heart and blood vessels. Drugs called ACE inhibitors and angiotensin-2 receptor antagonists are used to treat high blood pressure (hypertension), as are beta blockers, calcium channel blockers, diuretics, and other medications.

Antihypertensive drugs are those that are prescribed to reduce high blood pressure. They work by reducing the pressure exerted by the blood on the walls of the blood vessels. Answer and Explanation.